Nandrolone decanoate: the main action and the side effects of progestin
Nandrolone (also sold under the trademarks Retabolil, Deca Durabolin, DECAVER, Libol- 100, Decadubol-100, Nandroject-200, SP NANDROLONE-D, the chemical name – 19-nortestosterone) – anabolic steroid, which is present in the blood of every human being as a natural component in small quantities. Nandrolone is most often sold in a form decanoate, at least in the form phenylpropionate. Deca Durabolin first appeared on the market in 1962 and is one of the most popular steroids in recent decades, earning a reputation for severe anabolic activity and a relatively low incidence of side effects.
Retabolil still sold in pharmacies (from the company Gedeon Richter of veins, 50 mg / mL ampoules). Sold by prescription form form N 148-1 / y-88.
Structurally nandrolone differs from testosterone in the absence of carbon 19 position (hence the name 19-nortestosterone), and this makes it more similar to progestins. Due to its nature progestin, Retabolilum exhibits minimal androgenic activity significantly as compared to testosterone, however, the interaction with the progesterone receptor entails a number of side effects, which will be described below.
Another difference is that the testosterone in the body is gradually converted by the enzyme 5 alpha-reductase in potent androgen – dihydrotestosterone, which is responsible for development of the majority of side effects. Nandrolone is contrary converted 5-alpha reductase in a very weak androgen – dihydronandrolone that virtually no effect on the body and does not cause side effects. However, this may be one reason for reduction of libido during rate (due to a decrease of blood levels of androgens). I should add that dihydronandrolone sometimes included in some anabolic supplements, although much good is not.
- Severe muscle growth (at a rate you can collect up to 8 kg of muscle mass with minimal rollback phenomenon)
- Strengthen bones (previously used to treat osteoporosis) and ligaments (stimulates collagen synthesis)
- Elimination of joint pain, due to increased production of synovial fluid (joint lubricant)
- Increased red cell blood, resulting in the improvement of oxygen transport
- Increase the immune defense (applies even in people with AIDS)
Nandrolone has a relatively low incidence of side effects. As a result, low androgenic activity, side effects such as acne, alopecia, hair growth hardly occur. Nevertheless, they may, as in the use of any steroid, but in the case of nandrolone this only happens when the recommended doses are exceeded several times.
Retabolil has a very low conversion rate into estrogen has been shown 5 times lower than testosterone. The highest level of conversion is observed in the liver, while the main place where the transformation (adipose tissue) is available for this process. Because of this, Deca Durabolin has no side effects associated with estrogen (gynecomastia, accumulation of fluid in the body). Estrogennnaya drug activity occurs only at very high doses.
The above properties explain why Deca Durabolin is one of the most popular anabolic steroids to date, including for men with the aim of gaining lean muscle. Also need to add that nandrolone is virtually a phenomenon of rollback.
It has been observed that nandrolone capable of binding to progestin receptors (approximately 20% of the injected material) is associated with a remote carbon atom in 19 position. Almost all of the 19-nor anabolic steroids exhibit progestin activity.
In addition, during the course sometimes there are: the rise in blood pressure, abdominal pain, irritability, headaches, depression and some other complications.
Progestin side effects
By binding to receptors of the pituitary progestin, Nandrolone causes increased production of prolactin and suppresses anadrol 50 mg the secretion of gonadotropins. Prolactin is largely similar to estrogen and its effect is decreased production of testosterone, a slight increase in fat mass and, in rare cases, gynecomastia.
Reducing the concentration of testosterone in the blood and activating the progesterone receptor may very often lead to a decrease in libido is restored within a month after the course (called Deca-Dick, from the English. Deca Dick).
Progestin activity and its consequences (particularly sluggish erection, inhibition of sexual desire, and rarely gynecomastia) – is probably the main and very bad lack of Deca Durabolin, but it can be successfully prevented. For this purpose inhibitors of prolactin: bromocriptine, or more modern and secure – cabergoline (Dostinex). These drugs significantly increase sexual desire during the course (and beyond), enhance orgasm and shorten recovery time between sexual acts .. It has also been shown that the activity has antiprogestinovoy anabolic drug Winstrol (research Ellis AJ, Cawston TE, 1994), so they very well combined together.
Effective dosages nandrolone starting with 200 mg per week and leave almost … “infinity”. There are cases of nandrolone decanoate professional level athletes in dosages of about 800 mg per day. But Needless to bother with such doses – most of you are unlikely to reach a professional level – the upper limit of consumption of nandrolone establish 1000 mg per week.
On the basis of a sufficiently long half-life of nandrolone decanoate, you can recommend it to the injection once every 7-8 days, although more frequent injections like nandrolone and other long-lived products to help create a more stable level of steroid in the blood.
Combination with other drugs
Solo Course Retabolilum or Deca has many disadvantages, such as loss of libido, slow activity, the suppression of natural testosterone, and others. These disadvantages can be eliminated if you add in the course of androgenic drugs. Well nandrolone is combined with the following medications:
- Winstrol (stanozolol) – is very well combined with the drug, as has antiprogestinovoy activity (it prevents the development of Deca-Dick, increases libido, reduces the risk of gynecomastia, and others.)
- Testosterone (Sustanon, enanthate, cypionate, propionate) – to set the masses. Typically used 200-400 mg 1 time a week or Retabolilum Deca and 500-750 mg 1 time per week of testosterone.
· Methandrostenolone or methandienone – to set the masses, with 200-400 mg 1 time a week or Retabolilum Deca and 30-50 mg of methandrostenolone or methandienone every day